The Brain is highly intelligent and develops plans for global domination and he will use all sorts of methods from politics to inventions to achieve his mission. Brain’s name is revealed in “Project B.R.A.I.N.” to result from the acronym for “Biological Recombinant Algorithmic Intelligence Nexus”. His tail is bent like a staircase — he often uses it to pick the lock of the cage — and his head is large and wide, supposedly housing his abnormally large brain. He appears to be coldly unemotional and speaks in a deadpan manner.

Intellectually, Brain sees his inevitable rise to power as beneficial to the world rather than mere megalomania. An example of this being what he truly believes can be seen in Wakko’s Wish where he stated to Pinky “We’re on our way to fame, fortune and a world that’s a better place for all,” showing while he does envision himself becoming world leader, he wants to make everything greater for everyone.

One day Brain finds himself under the influence of hypnosis by a psychologist he had planned to manipulate for one of his schemes (none other than Sigmund Freud), it is revealed that Brain lived in a can with his parents when he was young. The researchers took him from his home, and the last he saw of it was a picture of the world on the side of the can. The psychologist speculates that Brain’s hunger to take over the world stems from needing to get his world back.